In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity

DNA replication is a complex and remarkably robust process: despite its inherent uncertainty, manifested through stochastic replication timing at a single-cell level, multiple control mechanisms ensure its accurate and timely completion across a population. Disruptions in these mechanisms lead to DN...

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Detalles Bibliográficos
Autores principales: Rapsomaniki, Maria Anna, Maxouri, Stella, Nathanailidou, Patroula, Garrastacho, Manuel Ramirez, Giakoumakis, Nickolaos Nikiforos, Taraviras, Stavros, Lygeros, John, Lygerou, Zoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846089/
https://www.ncbi.nlm.nih.gov/pubmed/33554116
http://dx.doi.org/10.1093/nargab/lqaa112

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