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Bacterial fitness landscapes stratify based on proteome allocation associated with discrete aero-types
The fitness landscape is a concept commonly used to describe evolution towards optimal phenotypes. It can be reduced to mechanistic detail using genome-scale models (GEMs) from systems biology. We use recently developed GEMs of Metabolism and protein Expression (ME-models) to study the distribution...
Autores principales: | Chen, Ke, Anand, Amitesh, Olson, Connor, Sandberg, Troy E., Gao, Ye, Mih, Nathan, Palsson, Bernhard O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846111/ https://www.ncbi.nlm.nih.gov/pubmed/33465077 http://dx.doi.org/10.1371/journal.pcbi.1008596 |
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