A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of Infective endocarditis

Bacterial binding to platelets is a key step in the development of infective endocarditis (IE). Sialic acid, a common terminal carbohydrate on host glycans, is the major receptor for streptococci on platelets. So far, all defined interactions between streptococci and sialic acid on platelets are med...

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Detalles Bibliográficos
Autores principales: Gaytán, Meztlli O., Singh, Anirudh K., Woodiga, Shireen A., Patel, Surina A., An, Seon-Sook, Vera-Ponce de León, Arturo, McGrath, Sean, Miller, Anthony R., Bush, Jocelyn M., van der Linden, Mark, Magrini, Vincent, Wilson, Richard K., Kitten, Todd, King, Samantha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846122/
https://www.ncbi.nlm.nih.gov/pubmed/33465168
http://dx.doi.org/10.1371/journal.ppat.1009222

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