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Optimal control of a fractional order model for the COVID – 19 pandemic
In this paper a fractional optimal control problem was formulated for the outbreak of COVID-19 using a mathematical model with fractional order derivative in the Caputo sense. The state and co-state equations were given and the best strategy to significantly reduce the spread of COVID-19 infections...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846236/ https://www.ncbi.nlm.nih.gov/pubmed/33551581 http://dx.doi.org/10.1016/j.chaos.2021.110678 |
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author | Baba, Bashir Abdullahi Bilgehan, Bulent |
author_facet | Baba, Bashir Abdullahi Bilgehan, Bulent |
author_sort | Baba, Bashir Abdullahi |
collection | PubMed |
description | In this paper a fractional optimal control problem was formulated for the outbreak of COVID-19 using a mathematical model with fractional order derivative in the Caputo sense. The state and co-state equations were given and the best strategy to significantly reduce the spread of COVID-19 infections was found by introducing two time-dependent control measures, [Formula: see text] (which represents the awareness campaign, lockdown, and all other measures that reduce the possibility of contacting the disease in susceptible human population) and [Formula: see text] (which represents quarantine, monitoring and treatment of infected humans). Numerical simulations were carried out using RK-4 to show the significance of the control functions. The exposed population in susceptible population is reduced by the factor ([Formula: see text]) due to the awareness and all other measures taken. Likewise, the infected population is reduced by a factor of ([Formula: see text]) due to the monitoring and treatment by health professionals. |
format | Online Article Text |
id | pubmed-7846236 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78462362021-02-01 Optimal control of a fractional order model for the COVID – 19 pandemic Baba, Bashir Abdullahi Bilgehan, Bulent Chaos Solitons Fractals Article In this paper a fractional optimal control problem was formulated for the outbreak of COVID-19 using a mathematical model with fractional order derivative in the Caputo sense. The state and co-state equations were given and the best strategy to significantly reduce the spread of COVID-19 infections was found by introducing two time-dependent control measures, [Formula: see text] (which represents the awareness campaign, lockdown, and all other measures that reduce the possibility of contacting the disease in susceptible human population) and [Formula: see text] (which represents quarantine, monitoring and treatment of infected humans). Numerical simulations were carried out using RK-4 to show the significance of the control functions. The exposed population in susceptible population is reduced by the factor ([Formula: see text]) due to the awareness and all other measures taken. Likewise, the infected population is reduced by a factor of ([Formula: see text]) due to the monitoring and treatment by health professionals. Elsevier Ltd. 2021-03 2021-01-29 /pmc/articles/PMC7846236/ /pubmed/33551581 http://dx.doi.org/10.1016/j.chaos.2021.110678 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Baba, Bashir Abdullahi Bilgehan, Bulent Optimal control of a fractional order model for the COVID – 19 pandemic |
title | Optimal control of a fractional order model for the COVID – 19 pandemic |
title_full | Optimal control of a fractional order model for the COVID – 19 pandemic |
title_fullStr | Optimal control of a fractional order model for the COVID – 19 pandemic |
title_full_unstemmed | Optimal control of a fractional order model for the COVID – 19 pandemic |
title_short | Optimal control of a fractional order model for the COVID – 19 pandemic |
title_sort | optimal control of a fractional order model for the covid – 19 pandemic |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846236/ https://www.ncbi.nlm.nih.gov/pubmed/33551581 http://dx.doi.org/10.1016/j.chaos.2021.110678 |
work_keys_str_mv | AT bababashirabdullahi optimalcontrolofafractionalordermodelforthecovid19pandemic AT bilgehanbulent optimalcontrolofafractionalordermodelforthecovid19pandemic |