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Direct control of CAR T cells through small molecule-regulated antibodies

Antibody-based therapeutics have experienced a rapid growth in recent years and are now utilized in various modalities spanning from conventional antibodies, antibody-drug conjugates, bispecific antibodies to chimeric antigen receptor (CAR) T cells. Many next generation antibody therapeutics achieve...

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Detalles Bibliográficos
Autores principales: Park, Spencer, Pascua, Edward, Lindquist, Kevin C., Kimberlin, Christopher, Deng, Xiaodi, Mak, Yvonne S. L., Melton, Zea, Johnson, Theodore O., Lin, Regina, Boldajipour, Bijan, Abraham, Robert T., Pons, Jaume, Sasu, Barbra Johnson, Van Blarcom, Thomas J., Chaparro-Riggers, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846603/
https://www.ncbi.nlm.nih.gov/pubmed/33514714
http://dx.doi.org/10.1038/s41467-020-20671-6

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