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Influence of cytochrome P450 2D6 polymorphism on hippocampal white matter and treatment response in schizophrenia

Cytochrome P450 2D6 (CYP2D6) is expressed at high levels in the brain and plays a considerable role in the biotransformation and neurotransmission of dopamine. This raises the question of whether CYP2D6 variations and its impact on the brain can confer susceptibility to schizophrenia. We investigate...

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Detalles Bibliográficos
Autores principales: Shin, Wonsuk, Bang, Minji, Kim, Anhye, Cho, Doo-Yeoun, Lee, Sang-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846743/
https://www.ncbi.nlm.nih.gov/pubmed/33514751
http://dx.doi.org/10.1038/s41537-020-00134-z