Multi-omic regulatory networks capture downstream effects of kinase inhibition in Mycobacterium tuberculosis

The ability of Mycobacterium tuberculosis (Mtb) to adapt to diverse stresses in its host environment is crucial for pathogenesis. Two essential Mtb serine/threonine protein kinases, PknA and PknB, regulate cell growth in response to environmental stimuli, but little is known about their downstream e...

Descripción completa

Detalles Bibliográficos
Autores principales: Young, Albert T., Carette, Xavier, Helmel, Michaela, Steen, Hanno, Husson, Robert N., Quackenbush, John, Platig, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846781/
https://www.ncbi.nlm.nih.gov/pubmed/33514755
http://dx.doi.org/10.1038/s41540-020-00164-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846781/
https://www.ncbi.nlm.nih.gov/pubmed/33514755
http://dx.doi.org/10.1038/s41540-020-00164-4

Ejemplares similares