Cargando…
Multi-omic regulatory networks capture downstream effects of kinase inhibition in Mycobacterium tuberculosis
The ability of Mycobacterium tuberculosis (Mtb) to adapt to diverse stresses in its host environment is crucial for pathogenesis. Two essential Mtb serine/threonine protein kinases, PknA and PknB, regulate cell growth in response to environmental stimuli, but little is known about their downstream e...
Autores principales: | Young, Albert T., Carette, Xavier, Helmel, Michaela, Steen, Hanno, Husson, Robert N., Quackenbush, John, Platig, John |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846781/ https://www.ncbi.nlm.nih.gov/pubmed/33514755 http://dx.doi.org/10.1038/s41540-020-00164-4 |
Ejemplares similares
-
Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface
por: Carette, Xavier, et al.
Publicado: (2018) -
Protein kinases PknA and PknB independently and coordinately regulate essential Mycobacterium tuberculosis physiologies and antimicrobial susceptibility
por: Zeng, Jumei, et al.
Publicado: (2020) -
Predicting genotype-specific gene regulatory networks
por: Weighill, Deborah, et al.
Publicado: (2022) -
Investigating essential gene function in Mycobacterium tuberculosis using an efficient CRISPR interference system
por: Singh, Atul K., et al.
Publicado: (2016) -
Influence of Plasmodium falciparum Calcium-Dependent Protein Kinase 5 (PfCDPK5) on the Late Schizont Stage Phosphoproteome
por: Blomqvist, Karin, et al.
Publicado: (2020)