PARP-1 and SIRT-1 are Interacted in Diabetic Nephropathy by Activating AMPK/PGC-1α Signaling Pathway

INTRODUCTION: Diabetic nephropathy (DN) is a metabolic disorder characterized by the accumulation of extracellular matrix (ECM). This study aims to investigate whether exists an interplay between poly (ADP-ribose) polymerase 1 (PARP-1) and sirtuin 1 (SIRT-1) in DN via AMP-activated protein kinase (A...

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Detalles Bibliográficos
Autores principales: Zhu, Hengmei, Fang, Zhi, Chen, Jiehui, Yang, Yun, Gan, Jiacheng, Luo, Liang, Zhan, Xiaojiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846827/
https://www.ncbi.nlm.nih.gov/pubmed/33531822
http://dx.doi.org/10.2147/DMSO.S291314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846827/
https://www.ncbi.nlm.nih.gov/pubmed/33531822
http://dx.doi.org/10.2147/DMSO.S291314

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