Evolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020

We sought to examine the trend (April–July) in the treatment patterns among hospitalized COVID-19 patients using the Premier Healthcare Database (PHD). In the analysis, we identified 53,264 patients from 302 hospitalsthat continuously provided inpatient data from April 1, 2020 to July 31, 2020 to th...

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Autores principales: Fan, Xiaozhou, Johnson, Barbara H, Johnston, Stephen S, Elangovanraaj, Nivesh, Coplan, Paul, Khanna, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846837/
https://www.ncbi.nlm.nih.gov/pubmed/33531828
http://dx.doi.org/10.2147/IJGM.S290118
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author Fan, Xiaozhou
Johnson, Barbara H
Johnston, Stephen S
Elangovanraaj, Nivesh
Coplan, Paul
Khanna, Rahul
author_facet Fan, Xiaozhou
Johnson, Barbara H
Johnston, Stephen S
Elangovanraaj, Nivesh
Coplan, Paul
Khanna, Rahul
author_sort Fan, Xiaozhou
collection PubMed
description We sought to examine the trend (April–July) in the treatment patterns among hospitalized COVID-19 patients using the Premier Healthcare Database (PHD). In the analysis, we identified 53,264 patients from 302 hospitalsthat continuously provided inpatient data from April 1, 2020 to July 31, 2020 to the PHD, a nationwide, population-based multihospital research database in the US. We used generalized estimating equations (GEE) models to assess changes in the proportion of therapies used during the study period. After adjusting for patient and provider factors, a decline in hydroxychloroquine and an increase in azithromycin and dexamethasone were observed among COVID-19 patients during the 4-month study period.
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spelling pubmed-78468372021-02-01 Evolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020 Fan, Xiaozhou Johnson, Barbara H Johnston, Stephen S Elangovanraaj, Nivesh Coplan, Paul Khanna, Rahul Int J Gen Med Short Report We sought to examine the trend (April–July) in the treatment patterns among hospitalized COVID-19 patients using the Premier Healthcare Database (PHD). In the analysis, we identified 53,264 patients from 302 hospitalsthat continuously provided inpatient data from April 1, 2020 to July 31, 2020 to the PHD, a nationwide, population-based multihospital research database in the US. We used generalized estimating equations (GEE) models to assess changes in the proportion of therapies used during the study period. After adjusting for patient and provider factors, a decline in hydroxychloroquine and an increase in azithromycin and dexamethasone were observed among COVID-19 patients during the 4-month study period. Dove 2021-01-25 /pmc/articles/PMC7846837/ /pubmed/33531828 http://dx.doi.org/10.2147/IJGM.S290118 Text en © 2021 Fan et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Short Report
Fan, Xiaozhou
Johnson, Barbara H
Johnston, Stephen S
Elangovanraaj, Nivesh
Coplan, Paul
Khanna, Rahul
Evolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020
title Evolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020
title_full Evolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020
title_fullStr Evolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020
title_full_unstemmed Evolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020
title_short Evolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020
title_sort evolving treatment patterns for hospitalized covid-19 patients in the united states in april 2020–july 2020
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846837/
https://www.ncbi.nlm.nih.gov/pubmed/33531828
http://dx.doi.org/10.2147/IJGM.S290118
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