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Chest CT findings in RT-PCR positive asymptomatic COVID-19 patients

PURPOSE: To investigate chest computed tomography (CT) findings in asymptomatic patients tested positive for coronavirus disease (COVID-19) by reverse transcription-polymerase chain reaction (RT-PCR). MATERIAL AND METHODS: The chest CT images of 64 patients with severe acute respiratory syndrome cor...

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Autores principales: Uysal, Emine, Kilinçer, Abidin, Cebeci, Hakan, Özer, Halil, Demir, Nazlım Aktuğ, Öztürk, Mehmet, Koplay, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846889/
https://www.ncbi.nlm.nih.gov/pubmed/33640789
http://dx.doi.org/10.1016/j.clinimag.2021.01.030
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author Uysal, Emine
Kilinçer, Abidin
Cebeci, Hakan
Özer, Halil
Demir, Nazlım Aktuğ
Öztürk, Mehmet
Koplay, Mustafa
author_facet Uysal, Emine
Kilinçer, Abidin
Cebeci, Hakan
Özer, Halil
Demir, Nazlım Aktuğ
Öztürk, Mehmet
Koplay, Mustafa
author_sort Uysal, Emine
collection PubMed
description PURPOSE: To investigate chest computed tomography (CT) findings in asymptomatic patients tested positive for coronavirus disease (COVID-19) by reverse transcription-polymerase chain reaction (RT-PCR). MATERIAL AND METHODS: The chest CT images of 64 patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who were RT-PCR test–positive but asymptomatic were retrospectively evaluated for the appearance and distribution of abnormal parenchymal findings. RESULTS: Of the 64 patients (mean age 59.4 ± 12; range 23–85), 42 (65%) were female, and 22 (35%) were male, and 16 (25%) of the patients had no abnormal findings on chest CT. Of the remaining 48 patients, lung involvement was bilateral in 32 (67%). Right upper lobe in 26 (54%), right middle lobe in 20 (42%), right lower lobe in 38 (79%), left upper lobe in 27 (56%), and left lower lobe were affected in 34 (71%) patients. The mean number of opacities detected in patients was 7.5 ± 5.7. The opacities were located only peripherally/subpleural in 22 (46%), only centrally/peribronchovascular in 5 (10%), and mixed in 21 (44%) patients. The frequency of pure ground glass opacities (GGO) was 63% GGO with a crazy-paving pattern or consolidation was 33%. Pure consolidation was detected in only two (4%) patients. Parenchymal opacities were only round in 27 (56%), only geographic demarcated in 3 (6%), only patchy in 2 (4%), and mixed in 16 (33%) patients. CONCLUSION: Chest CT was normal in only one-quarter of the asymptomatic patients. CT findings in asymptomatic COVID-19 patients were often peripherally located, mostly round-shaped GGO.
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spelling pubmed-78468892021-02-01 Chest CT findings in RT-PCR positive asymptomatic COVID-19 patients Uysal, Emine Kilinçer, Abidin Cebeci, Hakan Özer, Halil Demir, Nazlım Aktuğ Öztürk, Mehmet Koplay, Mustafa Clin Imaging Cardiothoracic Imaging PURPOSE: To investigate chest computed tomography (CT) findings in asymptomatic patients tested positive for coronavirus disease (COVID-19) by reverse transcription-polymerase chain reaction (RT-PCR). MATERIAL AND METHODS: The chest CT images of 64 patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who were RT-PCR test–positive but asymptomatic were retrospectively evaluated for the appearance and distribution of abnormal parenchymal findings. RESULTS: Of the 64 patients (mean age 59.4 ± 12; range 23–85), 42 (65%) were female, and 22 (35%) were male, and 16 (25%) of the patients had no abnormal findings on chest CT. Of the remaining 48 patients, lung involvement was bilateral in 32 (67%). Right upper lobe in 26 (54%), right middle lobe in 20 (42%), right lower lobe in 38 (79%), left upper lobe in 27 (56%), and left lower lobe were affected in 34 (71%) patients. The mean number of opacities detected in patients was 7.5 ± 5.7. The opacities were located only peripherally/subpleural in 22 (46%), only centrally/peribronchovascular in 5 (10%), and mixed in 21 (44%) patients. The frequency of pure ground glass opacities (GGO) was 63% GGO with a crazy-paving pattern or consolidation was 33%. Pure consolidation was detected in only two (4%) patients. Parenchymal opacities were only round in 27 (56%), only geographic demarcated in 3 (6%), only patchy in 2 (4%), and mixed in 16 (33%) patients. CONCLUSION: Chest CT was normal in only one-quarter of the asymptomatic patients. CT findings in asymptomatic COVID-19 patients were often peripherally located, mostly round-shaped GGO. Elsevier Inc. 2021-09 2021-01-30 /pmc/articles/PMC7846889/ /pubmed/33640789 http://dx.doi.org/10.1016/j.clinimag.2021.01.030 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Cardiothoracic Imaging
Uysal, Emine
Kilinçer, Abidin
Cebeci, Hakan
Özer, Halil
Demir, Nazlım Aktuğ
Öztürk, Mehmet
Koplay, Mustafa
Chest CT findings in RT-PCR positive asymptomatic COVID-19 patients
title Chest CT findings in RT-PCR positive asymptomatic COVID-19 patients
title_full Chest CT findings in RT-PCR positive asymptomatic COVID-19 patients
title_fullStr Chest CT findings in RT-PCR positive asymptomatic COVID-19 patients
title_full_unstemmed Chest CT findings in RT-PCR positive asymptomatic COVID-19 patients
title_short Chest CT findings in RT-PCR positive asymptomatic COVID-19 patients
title_sort chest ct findings in rt-pcr positive asymptomatic covid-19 patients
topic Cardiothoracic Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846889/
https://www.ncbi.nlm.nih.gov/pubmed/33640789
http://dx.doi.org/10.1016/j.clinimag.2021.01.030
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