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Remodeling hydrogen bond interactions results in relaxed specificity of Caspase-3

Caspase (or cysteinyl-aspartate specific proteases) enzymes play important roles in apoptosis and inflammation, and the non-identical but overlapping specificity profiles (that is, cleavage recognition sequence) direct cells to different fates. Although all caspases prefer aspartate at the P1 positi...

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Detalles Bibliográficos
Autores principales:	Yao, Liqi, Swartz, Paul, Hamilton, Paul T., Clark, A. Clay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846959/ https://www.ncbi.nlm.nih.gov/pubmed/33448281 http://dx.doi.org/10.1042/BSR20203495

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