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Computational analysis of Cyclin D1 gene SNPs and association with breast cancer

CCND1 encodes for Cyclin D1 protein and single-nucleotide polymorphisms (SNPs) can modulate its activity. In the present study, the impact of CCND1 SNPs on structure and/or function of Cyclin D1 protein using in silico tools was investigated. Our analysis revealed only one splice site SNP (c.1988+5G...

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Detalles Bibliográficos
Autores principales:	Aftab, Ayesha, Khan, Ranjha, Shah, Wasim, Azhar, Muhammad, Unar, Ahsanullah, Jafar Hussain, Hafiz Muhammad, Waqas, Ahmed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846961/ https://www.ncbi.nlm.nih.gov/pubmed/33438725 http://dx.doi.org/10.1042/BSR20202269

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