Outgrowth of a CSF3R-mutant clone drives a second myeloproliferative neoplasm in a chronic myeloid leukemia patient: a case report

BACKGROUND: Chronic myeloid leukemia (CML) and chronic neutrophilic leukemia (CNL) are two myeloproliferative neoplasms with mutually exclusive diagnostic criteria. A hallmark of CML is the Philadelphia chromosome (Ph), which results in a BCR-ABL1 fusion gene and constitutive tyrosine kinase activit...

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Detalles Bibliográficos
Autores principales: Carratt, Sarah A., Brewer, Diana, Maxson, Julia E., Druker, Brian J., Braun, Theodore P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847004/
https://www.ncbi.nlm.nih.gov/pubmed/33516272
http://dx.doi.org/10.1186/s40364-021-00261-4

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