Cargando…
Convergent lines of evidence support BIN1 as a risk gene of Alzheimer’s disease
Genome-wide association studies (GWAS) have identified several susceptibility loci of Alzheimer’s disease (AD), which were mainly located in noncoding regions of the genome. Meanwhile, the putative biological mechanisms underlying AD susceptibility loci were still unclear. At present, identifying th...
Autores principales: | Zhu, Jin, Liu, Xia, Yin, Hongtao, Gao, Yan, Yu, Hao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847034/ https://www.ncbi.nlm.nih.gov/pubmed/33516273 http://dx.doi.org/10.1186/s40246-021-00307-6 |
Ejemplares similares
-
CDK5 neutralizes the tumor suppressing effect of BIN1 via mediating phosphorylation of c-MYC at Ser-62 site in NSCLC
por: Zhang, Xiangyu, et al.
Publicado: (2019) -
Pathogenic convergence of CNVs in genes functionally associated to a severe neuromotor developmental delay syndrome
por: García-Hernández, Juan L., et al.
Publicado: (2021) -
Alzheimer’s disease risk gene BIN1 induces Tau-dependent network hyperexcitability
por: Voskobiynyk, Yuliya, et al.
Publicado: (2020) -
The combined risk effect among BIN1,
CLU, and APOE genes in Alzheimer’s
disease
por: dos Santos, Lígia Ramos, et al.
Publicado: (2020) -
MicroRNA-26a-mediated regulation of interleukin-2 expression in transformed avian lymphocyte lines
por: Xu, Hongtao, et al.
Publicado: (2010)