Cargando…

Mismatch negativity in older adults and its relationship with the cognitive and behavioral aspects of central auditory processing

OBJECTIVES: This study aimed to describe and compare the performance of older adults with normal hearing and hearing impairments in mismatch negativity (MMN), correlate MMN with cognitive tasks and central auditory processing (CAP), and identify normal values for MMN in older adults. METHODS: This s...

Descripción completa

Detalles Bibliográficos
Autores principales: Brückmann, Mirtes, Pagliarin, Karina Carlesso, Garcia, Michele Vargas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Medicina / USP 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847251/
https://www.ncbi.nlm.nih.gov/pubmed/33567043
http://dx.doi.org/10.6061/clinics/2021/e1830
_version_ 1783644894930141184
author Brückmann, Mirtes
Pagliarin, Karina Carlesso
Garcia, Michele Vargas
author_facet Brückmann, Mirtes
Pagliarin, Karina Carlesso
Garcia, Michele Vargas
author_sort Brückmann, Mirtes
collection PubMed
description OBJECTIVES: This study aimed to describe and compare the performance of older adults with normal hearing and hearing impairments in mismatch negativity (MMN), correlate MMN with cognitive tasks and central auditory processing (CAP), and identify normal values for MMN in older adults. METHODS: This study had 54 participants. The Montreal Cognitive Assessment (MoCA) was used to assess cognition and the random gap detection test (RGDT), dichotic digit test (DDT), and speech to noise (SN) test were used to evaluate CAP. MMN was elicited with the verbal stimulus /da/ (frequent) and /ta/ (rare), and the latency, amplitude, duration, and area were analyzed. RESULTS: When comparing the normal-hearing group to those with hearing loss, there was no significant difference in MMN. When correlating MMN with MoCA, RGDT, DDT, and the SN test, there was a weak correlation between the MMN amplitude and the RGDT and DDT. When comparing the MMN of participants with normal and altered cognitive aspects and those with normal and altered DDT, the MMN duration was found to be affected by the DDT. The mean latency value of the MMN in the normal-hearing group was 199.8 ms, the amplitude was -2.2 µV, area was 116.1 µV/ms, and duration was 81.2 ms. CONCLUSION: Mild hearing loss did not influence MMN. There was no correlation between MMN and cognitive aspects, and there were weak correlations with CAP. Alterations in CAP led to longer durations in MMN. Normal values for MMN in adults aged between 60 and 77 years were generated.
format Online
Article
Text
id pubmed-7847251
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Faculdade de Medicina / USP
record_format MEDLINE/PubMed
spelling pubmed-78472512021-02-05 Mismatch negativity in older adults and its relationship with the cognitive and behavioral aspects of central auditory processing Brückmann, Mirtes Pagliarin, Karina Carlesso Garcia, Michele Vargas Clinics (Sao Paulo) Original Article OBJECTIVES: This study aimed to describe and compare the performance of older adults with normal hearing and hearing impairments in mismatch negativity (MMN), correlate MMN with cognitive tasks and central auditory processing (CAP), and identify normal values for MMN in older adults. METHODS: This study had 54 participants. The Montreal Cognitive Assessment (MoCA) was used to assess cognition and the random gap detection test (RGDT), dichotic digit test (DDT), and speech to noise (SN) test were used to evaluate CAP. MMN was elicited with the verbal stimulus /da/ (frequent) and /ta/ (rare), and the latency, amplitude, duration, and area were analyzed. RESULTS: When comparing the normal-hearing group to those with hearing loss, there was no significant difference in MMN. When correlating MMN with MoCA, RGDT, DDT, and the SN test, there was a weak correlation between the MMN amplitude and the RGDT and DDT. When comparing the MMN of participants with normal and altered cognitive aspects and those with normal and altered DDT, the MMN duration was found to be affected by the DDT. The mean latency value of the MMN in the normal-hearing group was 199.8 ms, the amplitude was -2.2 µV, area was 116.1 µV/ms, and duration was 81.2 ms. CONCLUSION: Mild hearing loss did not influence MMN. There was no correlation between MMN and cognitive aspects, and there were weak correlations with CAP. Alterations in CAP led to longer durations in MMN. Normal values for MMN in adults aged between 60 and 77 years were generated. Faculdade de Medicina / USP 2021-02-01 2021 /pmc/articles/PMC7847251/ /pubmed/33567043 http://dx.doi.org/10.6061/clinics/2021/e1830 Text en Copyright © 2021 CLINICS http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.
spellingShingle Original Article
Brückmann, Mirtes
Pagliarin, Karina Carlesso
Garcia, Michele Vargas
Mismatch negativity in older adults and its relationship with the cognitive and behavioral aspects of central auditory processing
title Mismatch negativity in older adults and its relationship with the cognitive and behavioral aspects of central auditory processing
title_full Mismatch negativity in older adults and its relationship with the cognitive and behavioral aspects of central auditory processing
title_fullStr Mismatch negativity in older adults and its relationship with the cognitive and behavioral aspects of central auditory processing
title_full_unstemmed Mismatch negativity in older adults and its relationship with the cognitive and behavioral aspects of central auditory processing
title_short Mismatch negativity in older adults and its relationship with the cognitive and behavioral aspects of central auditory processing
title_sort mismatch negativity in older adults and its relationship with the cognitive and behavioral aspects of central auditory processing
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847251/
https://www.ncbi.nlm.nih.gov/pubmed/33567043
http://dx.doi.org/10.6061/clinics/2021/e1830
work_keys_str_mv AT bruckmannmirtes mismatchnegativityinolderadultsanditsrelationshipwiththecognitiveandbehavioralaspectsofcentralauditoryprocessing
AT pagliarinkarinacarlesso mismatchnegativityinolderadultsanditsrelationshipwiththecognitiveandbehavioralaspectsofcentralauditoryprocessing
AT garciamichelevargas mismatchnegativityinolderadultsanditsrelationshipwiththecognitiveandbehavioralaspectsofcentralauditoryprocessing