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A New Implementation of Genome Rearrangement Problem
Unsigned reverse genome rearrangement is an important part of bioinformatics research, which is widely used in biological similarity and homology analysis, revealing biological inheritance, variation, and evolution. Branch and bound, simulated annealing, and other algorithms in unsigned reverse geno...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847324/ https://www.ncbi.nlm.nih.gov/pubmed/33552456 http://dx.doi.org/10.1155/2021/6692775 |
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author | Jing, Xiaoqian Shi, Haihe |
author_facet | Jing, Xiaoqian Shi, Haihe |
author_sort | Jing, Xiaoqian |
collection | PubMed |
description | Unsigned reverse genome rearrangement is an important part of bioinformatics research, which is widely used in biological similarity and homology analysis, revealing biological inheritance, variation, and evolution. Branch and bound, simulated annealing, and other algorithms in unsigned reverse genome rearrangement algorithm are rare in practical application because of their huge time and space consumption, and greedy algorithms are mostly used at present. By deeply analyzing the domain of unsigned reverse genome rearrangement algorithm based on greedy strategy (unsigned reverse genome rearrangement algorithm (URGRA) based on greedy strategy), the domain features are modeled, and the URGRA algorithm components are interactively designed according to the production programming method. With the support of the PAR platform, the algorithm component library of the URGRA is formally realized, and the concrete algorithm is generated by assembly, which improves the reliability of the assembly algorithm. |
format | Online Article Text |
id | pubmed-7847324 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-78473242021-02-04 A New Implementation of Genome Rearrangement Problem Jing, Xiaoqian Shi, Haihe J Healthc Eng Research Article Unsigned reverse genome rearrangement is an important part of bioinformatics research, which is widely used in biological similarity and homology analysis, revealing biological inheritance, variation, and evolution. Branch and bound, simulated annealing, and other algorithms in unsigned reverse genome rearrangement algorithm are rare in practical application because of their huge time and space consumption, and greedy algorithms are mostly used at present. By deeply analyzing the domain of unsigned reverse genome rearrangement algorithm based on greedy strategy (unsigned reverse genome rearrangement algorithm (URGRA) based on greedy strategy), the domain features are modeled, and the URGRA algorithm components are interactively designed according to the production programming method. With the support of the PAR platform, the algorithm component library of the URGRA is formally realized, and the concrete algorithm is generated by assembly, which improves the reliability of the assembly algorithm. Hindawi 2021-01-23 /pmc/articles/PMC7847324/ /pubmed/33552456 http://dx.doi.org/10.1155/2021/6692775 Text en Copyright © 2021 Xiaoqian Jing and Haihe Shi. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Jing, Xiaoqian Shi, Haihe A New Implementation of Genome Rearrangement Problem |
title | A New Implementation of Genome Rearrangement Problem |
title_full | A New Implementation of Genome Rearrangement Problem |
title_fullStr | A New Implementation of Genome Rearrangement Problem |
title_full_unstemmed | A New Implementation of Genome Rearrangement Problem |
title_short | A New Implementation of Genome Rearrangement Problem |
title_sort | new implementation of genome rearrangement problem |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847324/ https://www.ncbi.nlm.nih.gov/pubmed/33552456 http://dx.doi.org/10.1155/2021/6692775 |
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