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A New Implementation of Genome Rearrangement Problem

Unsigned reverse genome rearrangement is an important part of bioinformatics research, which is widely used in biological similarity and homology analysis, revealing biological inheritance, variation, and evolution. Branch and bound, simulated annealing, and other algorithms in unsigned reverse geno...

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Detalles Bibliográficos
Autores principales: Jing, Xiaoqian, Shi, Haihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847324/
https://www.ncbi.nlm.nih.gov/pubmed/33552456
http://dx.doi.org/10.1155/2021/6692775
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author Jing, Xiaoqian
Shi, Haihe
author_facet Jing, Xiaoqian
Shi, Haihe
author_sort Jing, Xiaoqian
collection PubMed
description Unsigned reverse genome rearrangement is an important part of bioinformatics research, which is widely used in biological similarity and homology analysis, revealing biological inheritance, variation, and evolution. Branch and bound, simulated annealing, and other algorithms in unsigned reverse genome rearrangement algorithm are rare in practical application because of their huge time and space consumption, and greedy algorithms are mostly used at present. By deeply analyzing the domain of unsigned reverse genome rearrangement algorithm based on greedy strategy (unsigned reverse genome rearrangement algorithm (URGRA) based on greedy strategy), the domain features are modeled, and the URGRA algorithm components are interactively designed according to the production programming method. With the support of the PAR platform, the algorithm component library of the URGRA is formally realized, and the concrete algorithm is generated by assembly, which improves the reliability of the assembly algorithm.
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spelling pubmed-78473242021-02-04 A New Implementation of Genome Rearrangement Problem Jing, Xiaoqian Shi, Haihe J Healthc Eng Research Article Unsigned reverse genome rearrangement is an important part of bioinformatics research, which is widely used in biological similarity and homology analysis, revealing biological inheritance, variation, and evolution. Branch and bound, simulated annealing, and other algorithms in unsigned reverse genome rearrangement algorithm are rare in practical application because of their huge time and space consumption, and greedy algorithms are mostly used at present. By deeply analyzing the domain of unsigned reverse genome rearrangement algorithm based on greedy strategy (unsigned reverse genome rearrangement algorithm (URGRA) based on greedy strategy), the domain features are modeled, and the URGRA algorithm components are interactively designed according to the production programming method. With the support of the PAR platform, the algorithm component library of the URGRA is formally realized, and the concrete algorithm is generated by assembly, which improves the reliability of the assembly algorithm. Hindawi 2021-01-23 /pmc/articles/PMC7847324/ /pubmed/33552456 http://dx.doi.org/10.1155/2021/6692775 Text en Copyright © 2021 Xiaoqian Jing and Haihe Shi. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Jing, Xiaoqian
Shi, Haihe
A New Implementation of Genome Rearrangement Problem
title A New Implementation of Genome Rearrangement Problem
title_full A New Implementation of Genome Rearrangement Problem
title_fullStr A New Implementation of Genome Rearrangement Problem
title_full_unstemmed A New Implementation of Genome Rearrangement Problem
title_short A New Implementation of Genome Rearrangement Problem
title_sort new implementation of genome rearrangement problem
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847324/
https://www.ncbi.nlm.nih.gov/pubmed/33552456
http://dx.doi.org/10.1155/2021/6692775
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