Chondrosarcoma of the Skull Base: A Case Study and Literature Review

Chondrosarcomas (CSs) are rare malignant tumors composed of cells derived from the transformed chondrocytes. Only 2% of the total cases of CS are found at the skull base, thus representing a 0.1-0.2% prevalence. We present the case of a patient with CS at the middle cranial fossa who was admitted fo...

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Autores principales: Konovalov, Anton, Shekhtman, Oleg, Shekhtman, Anastasia P, Bezborodova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Neurosurgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847484/
https://www.ncbi.nlm.nih.gov/pubmed/33659104
http://dx.doi.org/10.7759/cureus.12412
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author Konovalov, Anton
Shekhtman, Oleg
Shekhtman, Anastasia P
Bezborodova, Tatyana
author_facet Konovalov, Anton
Shekhtman, Oleg
Shekhtman, Anastasia P
Bezborodova, Tatyana
author_sort Konovalov, Anton
collection PubMed
description Chondrosarcomas (CSs) are rare malignant tumors composed of cells derived from the transformed chondrocytes. Only 2% of the total cases of CS are found at the skull base, thus representing a 0.1-0.2% prevalence. We present the case of a patient with CS at the middle cranial fossa who was admitted for surgery to the Burdenko National Medical Research Center of Neurosurgery. In addition, we engage in a review of the literature to discuss the current approaches to the diagnostics and surgery of CS and delve deep into its embryo- and oncogenesis.
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spelling pubmed-78474842021-03-02 Chondrosarcoma of the Skull Base: A Case Study and Literature Review Konovalov, Anton Shekhtman, Oleg Shekhtman, Anastasia P Bezborodova, Tatyana Cureus Neurosurgery Chondrosarcomas (CSs) are rare malignant tumors composed of cells derived from the transformed chondrocytes. Only 2% of the total cases of CS are found at the skull base, thus representing a 0.1-0.2% prevalence. We present the case of a patient with CS at the middle cranial fossa who was admitted for surgery to the Burdenko National Medical Research Center of Neurosurgery. In addition, we engage in a review of the literature to discuss the current approaches to the diagnostics and surgery of CS and delve deep into its embryo- and oncogenesis. Cureus 2020-12-31 /pmc/articles/PMC7847484/ /pubmed/33659104 http://dx.doi.org/10.7759/cureus.12412 Text en Copyright © 2020, Konovalov et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurosurgery
Konovalov, Anton
Shekhtman, Oleg
Shekhtman, Anastasia P
Bezborodova, Tatyana
Chondrosarcoma of the Skull Base: A Case Study and Literature Review
title Chondrosarcoma of the Skull Base: A Case Study and Literature Review
title_full Chondrosarcoma of the Skull Base: A Case Study and Literature Review
title_fullStr Chondrosarcoma of the Skull Base: A Case Study and Literature Review
title_full_unstemmed Chondrosarcoma of the Skull Base: A Case Study and Literature Review
title_short Chondrosarcoma of the Skull Base: A Case Study and Literature Review
title_sort chondrosarcoma of the skull base: a case study and literature review
topic Neurosurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847484/
https://www.ncbi.nlm.nih.gov/pubmed/33659104
http://dx.doi.org/10.7759/cureus.12412
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AT bezborodovatatyana chondrosarcomaoftheskullbaseacasestudyandliteraturereview

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