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The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia
BACKGROUND: The role of the immune system in stroke is well-recognised. Fingolimod, an immunomodulatory agent licensed for the management of relapsing-remitting multiple sclerosis, has been shown to provide benefit in rodent models of stroke. Its mechanism of action, however, remains unclear. We hyp...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847573/ https://www.ncbi.nlm.nih.gov/pubmed/33516262 http://dx.doi.org/10.1186/s12974-021-02083-5 |