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The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia

BACKGROUND: The role of the immune system in stroke is well-recognised. Fingolimod, an immunomodulatory agent licensed for the management of relapsing-remitting multiple sclerosis, has been shown to provide benefit in rodent models of stroke. Its mechanism of action, however, remains unclear. We hyp...

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Detalles Bibliográficos
Autores principales: Malone, Kyle, Diaz Diaz, Andrea C., Shearer, Jennifer A., Moore, Anne C., Waeber, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847573/
https://www.ncbi.nlm.nih.gov/pubmed/33516262
http://dx.doi.org/10.1186/s12974-021-02083-5