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Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH)

BACKGROUND: Microglia-driven cerebral spreading inflammation is a key contributor to secondary brain injury after SAH. Genetic depletion or deactivation of microglia has been shown to ameliorate neuronal cell death. Therefore, clinically feasible anti-inflammatory approaches counteracting microglia...

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Detalles Bibliográficos
Autores principales:	Heinz, Rebecca, Brandenburg, Susan, Nieminen-Kelhä, Melina, Kremenetskaia, Irina, Boehm-Sturm, Philipp, Vajkoczy, Peter, Schneider, Ulf C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847606/ https://www.ncbi.nlm.nih.gov/pubmed/33516246 http://dx.doi.org/10.1186/s12974-021-02085-3

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