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Comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer

Purpose: The aim of this study was to compare survival outcomes of open radical hysterectomy and minimally invasive radical hysterectomy (MIS) in early stage cervical cancer. Methods: A retrospective analysis of 148 patients with stage IB1 - IIA2 cervical cancer who underwent either minimally invasi...

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Autores principales: Kim, Sang Il, Lee, Jiwoo, Hong, Jiyun, Lee, Sung Jong, Park, Dong Choon, Yoon, Joo Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847619/
https://www.ncbi.nlm.nih.gov/pubmed/33526992
http://dx.doi.org/10.7150/ijms.55017
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author Kim, Sang Il
Lee, Jiwoo
Hong, Jiyun
Lee, Sung Jong
Park, Dong Choon
Yoon, Joo Hee
author_facet Kim, Sang Il
Lee, Jiwoo
Hong, Jiyun
Lee, Sung Jong
Park, Dong Choon
Yoon, Joo Hee
author_sort Kim, Sang Il
collection PubMed
description Purpose: The aim of this study was to compare survival outcomes of open radical hysterectomy and minimally invasive radical hysterectomy (MIS) in early stage cervical cancer. Methods: A retrospective analysis of 148 patients with stage IB1 - IIA2 cervical cancer who underwent either minimally invasive or open radical hysterectomy. Tumor characteristics, recurrence rate, disease-free survival (DFS), and overall survival (OS) were compared according to surgical approach. Results: In total, 110 and 38 patients were assigned to open surgery and MIS groups. After a medical follow-up of 42.1 months, the groups showed similar survival outcomes (recurrence rate, DFS, and OS). However, in patients with tumor size >2 cm, recurrence rate was significantly higher in MIS group (22.5% vs 0%; p=0.008). And in patients with tumor size >2 cm, MIS group showed significantly poorer DFS than open surgery group (p=0.017), although OS was similar between the two groups (p=0.252). Conclusion: In patients with tumor size >2 cm, MIS was associated with higher recurrence rates and poorer DFS than open surgery. However, in patients with tumor size ≤2 cm, MIS did not seem to compromise oncologic outcomes.
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spelling pubmed-78476192021-01-31 Comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer Kim, Sang Il Lee, Jiwoo Hong, Jiyun Lee, Sung Jong Park, Dong Choon Yoon, Joo Hee Int J Med Sci Research Paper Purpose: The aim of this study was to compare survival outcomes of open radical hysterectomy and minimally invasive radical hysterectomy (MIS) in early stage cervical cancer. Methods: A retrospective analysis of 148 patients with stage IB1 - IIA2 cervical cancer who underwent either minimally invasive or open radical hysterectomy. Tumor characteristics, recurrence rate, disease-free survival (DFS), and overall survival (OS) were compared according to surgical approach. Results: In total, 110 and 38 patients were assigned to open surgery and MIS groups. After a medical follow-up of 42.1 months, the groups showed similar survival outcomes (recurrence rate, DFS, and OS). However, in patients with tumor size >2 cm, recurrence rate was significantly higher in MIS group (22.5% vs 0%; p=0.008). And in patients with tumor size >2 cm, MIS group showed significantly poorer DFS than open surgery group (p=0.017), although OS was similar between the two groups (p=0.252). Conclusion: In patients with tumor size >2 cm, MIS was associated with higher recurrence rates and poorer DFS than open surgery. However, in patients with tumor size ≤2 cm, MIS did not seem to compromise oncologic outcomes. Ivyspring International Publisher 2021-01-19 /pmc/articles/PMC7847619/ /pubmed/33526992 http://dx.doi.org/10.7150/ijms.55017 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Research Paper
Kim, Sang Il
Lee, Jiwoo
Hong, Jiyun
Lee, Sung Jong
Park, Dong Choon
Yoon, Joo Hee
Comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer
title Comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer
title_full Comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer
title_fullStr Comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer
title_full_unstemmed Comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer
title_short Comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer
title_sort comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847619/
https://www.ncbi.nlm.nih.gov/pubmed/33526992
http://dx.doi.org/10.7150/ijms.55017
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