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Minimally invasive surgery for patients with advanced stage endometrial cancer

Objective: Compare the oncologic outcomes of patients with advanced stage endometrial cancer who were staged by minimally invasive surgery with the outcomes of patients who underwent open surgery. Methods: Data from 138 patients with advanced stage endometrial cancer who were treated between January...

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Autores principales: Kim, Sang Il, Park, Dong Choon, Lee, Sung Jong, Yoo, Ji Geun, Song, Min Jong, Kim, Chan Joo, Lee, Hae Nam, Yoon, Joo Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847628/
https://www.ncbi.nlm.nih.gov/pubmed/33526975
http://dx.doi.org/10.7150/ijms.52293
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author Kim, Sang Il
Park, Dong Choon
Lee, Sung Jong
Yoo, Ji Geun
Song, Min Jong
Kim, Chan Joo
Lee, Hae Nam
Yoon, Joo Hee
author_facet Kim, Sang Il
Park, Dong Choon
Lee, Sung Jong
Yoo, Ji Geun
Song, Min Jong
Kim, Chan Joo
Lee, Hae Nam
Yoon, Joo Hee
author_sort Kim, Sang Il
collection PubMed
description Objective: Compare the oncologic outcomes of patients with advanced stage endometrial cancer who were staged by minimally invasive surgery with the outcomes of patients who underwent open surgery. Methods: Data from 138 patients with advanced stage endometrial cancer who were treated between January 2009 and January 2019 were reviewed. The patients' data were retrieved from five institutions. The patients were divided into two groups: those who underwent open surgery and those who underwent minimally invasive surgery. Tumor characteristics, recurrence rate, disease-free survival, and overall survival were compared according to surgical approach. Results: Among the 138 patients included in this study, 72 underwent open surgery (52.2%) and 66 underwent MIS (47.8%). In patients with advanced-stage endometrial cancer, the recurrence rate was significantly higher among those who underwent open surgery (43.1% vs. 25.8%, p = 0.033). Patients with advanced-stage endometrial cancer who underwent open surgery had a significantly lower disease-free survival (p = 0.029) than those who underwent minimally invasive surgery, however, the overall survival (p = 0.051) was similar between the two groups. Conclusion: Minimally invasive surgery showed better survival outcomes when compared to open surgery in advanced-stage EC patients irrespective of the histologic type.
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spelling pubmed-78476282021-01-31 Minimally invasive surgery for patients with advanced stage endometrial cancer Kim, Sang Il Park, Dong Choon Lee, Sung Jong Yoo, Ji Geun Song, Min Jong Kim, Chan Joo Lee, Hae Nam Yoon, Joo Hee Int J Med Sci Research Paper Objective: Compare the oncologic outcomes of patients with advanced stage endometrial cancer who were staged by minimally invasive surgery with the outcomes of patients who underwent open surgery. Methods: Data from 138 patients with advanced stage endometrial cancer who were treated between January 2009 and January 2019 were reviewed. The patients' data were retrieved from five institutions. The patients were divided into two groups: those who underwent open surgery and those who underwent minimally invasive surgery. Tumor characteristics, recurrence rate, disease-free survival, and overall survival were compared according to surgical approach. Results: Among the 138 patients included in this study, 72 underwent open surgery (52.2%) and 66 underwent MIS (47.8%). In patients with advanced-stage endometrial cancer, the recurrence rate was significantly higher among those who underwent open surgery (43.1% vs. 25.8%, p = 0.033). Patients with advanced-stage endometrial cancer who underwent open surgery had a significantly lower disease-free survival (p = 0.029) than those who underwent minimally invasive surgery, however, the overall survival (p = 0.051) was similar between the two groups. Conclusion: Minimally invasive surgery showed better survival outcomes when compared to open surgery in advanced-stage EC patients irrespective of the histologic type. Ivyspring International Publisher 2021-01-01 /pmc/articles/PMC7847628/ /pubmed/33526975 http://dx.doi.org/10.7150/ijms.52293 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Research Paper
Kim, Sang Il
Park, Dong Choon
Lee, Sung Jong
Yoo, Ji Geun
Song, Min Jong
Kim, Chan Joo
Lee, Hae Nam
Yoon, Joo Hee
Minimally invasive surgery for patients with advanced stage endometrial cancer
title Minimally invasive surgery for patients with advanced stage endometrial cancer
title_full Minimally invasive surgery for patients with advanced stage endometrial cancer
title_fullStr Minimally invasive surgery for patients with advanced stage endometrial cancer
title_full_unstemmed Minimally invasive surgery for patients with advanced stage endometrial cancer
title_short Minimally invasive surgery for patients with advanced stage endometrial cancer
title_sort minimally invasive surgery for patients with advanced stage endometrial cancer
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847628/
https://www.ncbi.nlm.nih.gov/pubmed/33526975
http://dx.doi.org/10.7150/ijms.52293
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