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Targeting miR-21 with NL101 blocks c-Myc/Mxd1 loop and inhibits the growth of B cell lymphoma
Background: NL101 has shown activities against multiple myeloma and acute myeloid leukemia, but its anti-lymphoma activity remains unknown. The transcription factor c-Myc is frequently dysregulated in aggressive B cell lymphomas such as double-hit lymphoma, for which the standard of care is still la...
Autores principales: | Li, Shu, He, Xin, Gan, Yichao, Zhang, Jiawei, Gao, Feiqiong, Lin, Limin, Qiu, Xi, Yu, Teng, Zhang, Xuzhao, Chen, Panpan, Tong, Jiefeng, Qian, Wenbin, Xu, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847677/ https://www.ncbi.nlm.nih.gov/pubmed/33537096 http://dx.doi.org/10.7150/thno.53561 |
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