Cargando…

Nasal administration of mitochondria reverses chemotherapy-induced cognitive deficits

Up to seventy-five percent of patients treated for cancer suffer from cognitive deficits which can persist for months to decades, severely impairing quality of life. Although the number of cancer survivors is increasing tremendously, no efficacious interventions exist. Cisplatin, most commonly emplo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alexander, Jenolyn F., Seua, Alexandre V., Arroyo, Luis D., Ray, Pradipta R., Wangzhou, Andi, Heiβ-Lückemann, Laura, Schedlowski, Manfred, Price, Theodore J., Kavelaars, Annemieke, Heijnen, Cobi J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847685/ https://www.ncbi.nlm.nih.gov/pubmed/33537077 http://dx.doi.org/10.7150/thno.53474

Ejemplares similares

Bexarotene normalizes chemotherapy-induced myelin decompaction and reverses cognitive and sensorimotor deficits in mice
por: Chiang, Angie C. A., et al.
Publicado: (2020)

Nasal administration of mesenchymal stem cells prevents accelerated age-related tauopathy after chemotherapy in mice
por: Zamorano, Miriam, et al.
Publicado: (2023)

CD8(+) T cell–derived IL-13 increases macrophage IL-10 to resolve neuropathic pain
por: Singh, Susmita K., et al.
Publicado: (2022)

Cisplatin treatment induces attention deficits and impairs synaptic integrity in the prefrontal cortex in mice
por: Huo, XiaoJiao, et al.
Publicado: (2018)

Metformin Prevents Cisplatin-Induced Cognitive Impairment and Brain Damage in Mice
por: Zhou, Wenjun, et al.
Publicado: (2016)

Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b
por: Dulos, John, et al.
Publicado: (2005)

Intranasally Administered MSC-Derived Extracellular Vesicles Reverse Cisplatin-Induced Cognitive Impairment
por: Milutinovic, Bojana, et al.
Publicado: (2023)

Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin
por: Boukelmoune, Nabila, et al.
Publicado: (2018)

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment
por: Ma, Jiacheng, et al.
Publicado: (2018)

HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor Signaling
por: Zhang, Jixiang, et al.
Publicado: (2022)

Pharmacological Neuroprotection after Perinatal Hypoxic-Ischemic Brain Injury
por: Fan, Xiyong, et al.
Publicado: (2010)

CD3(+) T cells are critical for the resolution of comorbid inflammatory pain and depression-like behavior
por: Laumet, Geoffroy, et al.
Publicado: (2020)

The Anti-Diabetic Drug Metformin Protects against Chemotherapy-Induced Peripheral Neuropathy in a Mouse Model
por: Mao-Ying, Qi-Liang, et al.
Publicado: (2014)

Low GRK2 Underlies Hyperalgesic Priming by Glial Cell-Derived Neurotrophic Factor
por: Wang, Hui-Jing, et al.
Publicado: (2018)

Inhibition of Mitochondrial p53 Accumulation by PFT-μ Prevents Cisplatin-Induced Peripheral Neuropathy
por: Maj, Magdalena A., et al.
Publicado: (2017)

Nasal administration of mesenchymal stem cells restores cisplatin-induced cognitive impairment and brain damage in mice
por: Chiu, Gabriel S., et al.
Publicado: (2018)

T Cells as an Emerging Target for Chronic Pain Therapy
por: Laumet, Geoffroy, et al.
Publicado: (2019)

Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer
por: English, Krystal, et al.
Publicado: (2020)

Transcriptome Analysis of the Human Tibial Nerve Identifies Sexually Dimorphic Expression of Genes Involved in Pain, Inflammation, and Neuro-Immunity
por: Ray, Pradipta R., et al.
Publicado: (2019)

Type D Personality, Temperament, and Mental Health in Military Personnel Awaiting Deployment
por: Mommersteeg, Paula M. C., et al.
Publicado: (2010)

HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity
por: McAlpin, Blake R, et al.
Publicado: (2022)

The rodent endovascular puncture model of subarachnoid hemorrhage: mechanisms of brain damage and therapeutic strategies
por: Kooijman, Elke, et al.
Publicado: (2014)

IL-1β reactivity and the development of severe fatigue after military deployment: a longitudinal study
por: van Zuiden, Mirjam, et al.
Publicado: (2012)

Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1
por: Baameur, Faiza, et al.
Publicado: (2016)

TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain
por: Kasembeli, Moses M., et al.
Publicado: (2021)

Alleviation of paclitaxel-induced mechanical hypersensitivity and hyperalgesic priming with AMPK activators in male and female mice
por: Inyang, Kufreobong E., et al.
Publicado: (2019)

MicroRNA-124 as a novel treatment for persistent hyperalgesia
por: Willemen, Hanneke LDM, et al.
Publicado: (2012)

Intranasal Administration of Human MSC for Ischemic Brain Injury in the Mouse: In Vitro and In Vivo Neuroregenerative Functions
por: Donega, Vanessa, et al.
Publicado: (2014)

Targeting the A(3) adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice
por: Singh, Anand Kumar, et al.
Publicado: (2022)

Cytokine Production by Leukocytes of Military Personnel with Depressive Symptoms after Deployment to a Combat-Zone: A Prospective, Longitudinal Study
por: van Zuiden, Mirjam, et al.
Publicado: (2011)

Mechanisms of chemotherapy-induced behavioral toxicities
por: Vichaya, Elisabeth G., et al.
Publicado: (2015)

Endometrial Stromal Cells of Women with Recurrent Miscarriage Fail to Discriminate between High- and Low-Quality Human Embryos
por: Weimar, Charlotte H. E., et al.
Publicado: (2012)

Intranasal Mesenchymal Stem Cell Treatment for Neonatal Brain Damage: Long-Term Cognitive and Sensorimotor Improvement
por: Donega, Vanessa, et al.
Publicado: (2013)

Patient–reported fatigue prior to treatment is prognostic of survival in patients with acute myeloid leukemia
por: Lacourt, Tamara E., et al.
Publicado: (2018)

Assessment of long-term safety and efficacy of intranasal mesenchymal stem cell treatment for neonatal brain injury in the mouse
por: Donega, Vanessa, et al.
Publicado: (2015)

Treatment with the calcineurin inhibitor and immunosuppressant cyclosporine A impairs sensorimotor gating in Dark Agouti rats
por: Brosda, Jan, et al.
Publicado: (2020)

Dexamethasone Attenuates VEGF Expression and Inflammation but Not Barrier Dysfunction in a Murine Model of Ventilator–Induced Lung Injury
por: Hegeman, Maria A., et al.
Publicado: (2013)

Repeated Systemic Treatment with Rapamycin Affects Behavior and Amygdala Protein Expression in Rats
por: Hadamitzky, Martin, et al.
Publicado: (2018)

Angiopoietin-1 Treatment Reduces Inflammation but Does Not Prevent Ventilator-Induced Lung Injury
por: Hegeman, Maria A., et al.
Publicado: (2010)

Effects of Murine and Human Bone Marrow-Derived Mesenchymal Stem Cells on Cuprizone Induced Demyelination
por: Nessler, Jasmin, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_sdvmgh19btkl7rc85kp35o80kk