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Inhaled high molecular weight hyaluronan ameliorates respiratory failure in acute COPD exacerbation: a pilot study

BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) carry significant morbidity and mortality. AECOPD treatment remains limited. High molecular weight hyaluronan (HMW-HA) is a glycosaminoglycan sugar, which is a physiological constituent of the lung extracellular matrix...

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Detalles Bibliográficos
Autores principales: Galdi, Flavia, Pedone, Claudio, McGee, Christopher A., George, Margaret, Rice, Annette B., Hussain, Shah S., Vijaykumar, Kadambari, Boitet, Evan R., Tearney, Guillermo J., McGrath, John A., Brown, Audrey R., Rowe, Steven M., Incalzi, Raffaele A., Garantziotis, Stavros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847749/
https://www.ncbi.nlm.nih.gov/pubmed/33517896
http://dx.doi.org/10.1186/s12931-020-01610-x