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Inhaled high molecular weight hyaluronan ameliorates respiratory failure in acute COPD exacerbation: a pilot study
BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) carry significant morbidity and mortality. AECOPD treatment remains limited. High molecular weight hyaluronan (HMW-HA) is a glycosaminoglycan sugar, which is a physiological constituent of the lung extracellular matrix...
Autores principales: | Galdi, Flavia, Pedone, Claudio, McGee, Christopher A., George, Margaret, Rice, Annette B., Hussain, Shah S., Vijaykumar, Kadambari, Boitet, Evan R., Tearney, Guillermo J., McGrath, John A., Brown, Audrey R., Rowe, Steven M., Incalzi, Raffaele A., Garantziotis, Stavros |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847749/ https://www.ncbi.nlm.nih.gov/pubmed/33517896 http://dx.doi.org/10.1186/s12931-020-01610-x |
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