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Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells

BACKGROUND & AIMS: Tight junctions form a barrier to the paracellular passage of luminal antigens. Although most tight junction proteins reside within the apical tight junction complex, claudin-18 localizes mainly to the basolateral membrane where its contribution to paracellular ion transport i...

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Detalles Bibliográficos
Autores principales: Caron, Tyler J., Scott, Kathleen E., Sinha, Nishita, Muthupalani, Sureshkumar, Baqai, Mahnoor, Ang, Lay-Hong, Li, Yue, Turner, Jerrold R., Fox, James G., Hagen, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847960/
https://www.ncbi.nlm.nih.gov/pubmed/33069918
http://dx.doi.org/10.1016/j.jcmgh.2020.10.005