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Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells
BACKGROUND & AIMS: Tight junctions form a barrier to the paracellular passage of luminal antigens. Although most tight junction proteins reside within the apical tight junction complex, claudin-18 localizes mainly to the basolateral membrane where its contribution to paracellular ion transport i...
Autores principales: | Caron, Tyler J., Scott, Kathleen E., Sinha, Nishita, Muthupalani, Sureshkumar, Baqai, Mahnoor, Ang, Lay-Hong, Li, Yue, Turner, Jerrold R., Fox, James G., Hagen, Susan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847960/ https://www.ncbi.nlm.nih.gov/pubmed/33069918 http://dx.doi.org/10.1016/j.jcmgh.2020.10.005 |
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