A two-hit adversity model in developing rats reveals sex-specific impacts on prefrontal cortex structure and behavior

Adversity early in life substantially impacts prefrontal cortex (PFC) development and vulnerability to later-life psychopathology. Importantly, repeated adverse experiences throughout childhood increase the risk for PFC-mediated behavioral deficits more commonly in women. Evidence from animal models...

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Detalles Bibliográficos
Autores principales: Gildawie, Kelsea R., Ryll, Lilly M., Hexter, Jessica C., Peterzell, Shayna, Valentine, Alissa A., Brenhouse, Heather C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847967/
https://www.ncbi.nlm.nih.gov/pubmed/33515957
http://dx.doi.org/10.1016/j.dcn.2021.100924

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