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Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway

Tacrolimus-induced chronic nephrotoxicity (TIN) hinders its long-term use in patients. However, there are no drugs available in the clinic to relieve it at present. Astragaloside IV (AS-IV) is a saponin extract of the Astragalus which is widely used in the treatment of kidney disease. This study aim...

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Detalles Bibliográficos
Autores principales:	Gao, Ping, Du, Xiaoyi, Liu, Lili, Xu, Hua, Liu, Maochang, Guan, Xinlei, Zhang, Chengliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848072/ https://www.ncbi.nlm.nih.gov/pubmed/33536919 http://dx.doi.org/10.3389/fphar.2020.610102

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