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Metabolite Profiling of Dihydroartemisinin in Blood of Plasmodium-Infected and Healthy Mice Using UPLC-Q-TOF-MS(E)

Dihydroartemisinin (DHA) and its’ derivatives have been employed as the most powerful first-line drugs for malarial treatment for several decades. The metabolism of DHA has not been studied clearly. Previous reports were focused on the pharmacokinetics procedure of DHA in healthy rats. The metabolit...

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Detalles Bibliográficos
Autores principales:	Zhao, Yifan, Sun, Peng, Ma, Yue, Chang, Xiaoqiang, Chen, Xingyu, Ji, Xin, Bai, Yue, Zhang, Dong, Yang, Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848114/ https://www.ncbi.nlm.nih.gov/pubmed/33536920 http://dx.doi.org/10.3389/fphar.2020.614159

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