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Prolonged Withdrawal From Escalated Oxycodone Is Associated With Increased Expression of Glutamate Receptors in the Rat Hippocampus

People suffering from opioid use disorder (OUD) exhibit cognitive dysfunctions. Here, we investigated potential changes in the expression of glutamate receptors in rat hippocampi at 2 h and 31 days after the last session of oxycodone self-administration (SA). RNA extracted from the hippocampus was u...

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Detalles Bibliográficos
Autores principales: Salisbury, Aaron J., Blackwood, Christopher A., Cadet, Jean Lud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848144/
https://www.ncbi.nlm.nih.gov/pubmed/33536871
http://dx.doi.org/10.3389/fnins.2020.617973