Cargando…

Baicalin Ameliorates Pancreatic Fibrosis by Inhibiting the Activation of Pancreatic Stellate Cells in Mice with Chronic Pancreatitis

Pancreatic inflammation and fibrosis are typical pathological features in chronic pancreatitis (CP). Activated pancreatic stellate cells (PSCs) have been regarded as the core event in the development of pancreatic fibrosis and are considered to be the key target for treatment of CP. Baicalin (C(21)H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Jianwei, Duan, Lifang, Wu, Nan, Xu, Xiaofan, Xin, Jiaqi, Jiang, Shengnan, Zhang, Cheng, Zhang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848203/ https://www.ncbi.nlm.nih.gov/pubmed/33536916 http://dx.doi.org/10.3389/fphar.2020.607133

Ejemplares similares

Dachaihu decoction ameliorates pancreatic fibrosis by inhibiting macrophage infiltration in chronic pancreatitis
por: Duan, Li-Fang, et al.
Publicado: (2017)

The effects of nuclear factor‐kappa B in pancreatic stellate cells on inflammation and fibrosis of chronic pancreatitis
por: Wu, Nan, et al.
Publicado: (2020)

Targeting pancreatic stellate cells in chronic pancreatitis: Focus on therapeutic drugs and natural compounds
por: Wu, Yang, et al.
Publicado: (2022)

Rhein, a Natural Anthraquinone Derivative, Attenuates the Activation of Pancreatic Stellate Cells and Ameliorates Pancreatic Fibrosis in Mice with Experimental Chronic Pancreatitis
por: Tsang, Siu Wai, et al.
Publicado: (2013)

Aspirin Ameliorates Pancreatic Inflammation and Fibrosis by Inhibiting COX-2 Expression in Experimental Chronic Pancreatitis
por: Xu, Xiao-Fan, et al.
Publicado: (2022)

Retinoic Acid Ameliorates Pancreatic Fibrosis and Inhibits the Activation of Pancreatic Stellate Cells in Mice with Experimental Chronic Pancreatitis via Suppressing the Wnt/β-Catenin Signaling Pathway
por: Xiao, Wenqin, et al.
Publicado: (2015)

Arecae pericarpium water extract alleviates chronic pancreatitis by deactivating pancreatic stellate cells
por: Kweon, Bitna, et al.
Publicado: (2022)

Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
por: Xiao, Ying, et al.
Publicado: (2020)

Hic-5 is required for activation of pancreatic stellate cells and development of pancreatic fibrosis in chronic pancreatitis
por: Gao, Lin, et al.
Publicado: (2020)

Emodin Ameliorates Acute Pancreatitis-Associated Lung Injury Through Inhibiting the Alveolar Macrophages Pyroptosis
por: Wu, Xiajia, et al.
Publicado: (2022)

Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway
por: Cui, Lihua, et al.
Publicado: (2021)

Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage
por: Duan, Lining, et al.
Publicado: (2021)

L-Cysteine Administration Attenuates Pancreatic Fibrosis Induced by TNBS in Rats by Inhibiting the Activation of Pancreatic Stellate Cell
por: Yang, LiJuan, et al.
Publicado: (2012)

Pancreatic cancer-derived exosomes promoted pancreatic stellate cells recruitment by pancreatic cancer
por: Zhang, Yue-Feng, et al.
Publicado: (2019)

Pancreatic Stellate Cells and the Targeted Therapeutic Strategies in Chronic Pancreatitis
por: Chang, Man, et al.
Publicado: (2023)

Baicalin Prevents Myocardial Ischemia/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis
por: Fan, Zhenyu, et al.
Publicado: (2021)

Activated pancreatic stellate cells can impair pancreatic islet function in mice
por: Zang, Guangxiang, et al.
Publicado: (2015)

Functions of pancreatic stellate cell-derived soluble factors in the microenvironment of pancreatic ductal carcinoma
por: Wu, Qi, et al.
Publicado: (2017)

IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis
por: Ng, Benjamin, et al.
Publicado: (2022)

Puerarin Ameliorates Caerulein-Induced Chronic Pancreatitis via Inhibition of MAPK Signaling Pathway
por: Zeng, Xiang-Peng, et al.
Publicado: (2021)

HDAC inhibitors promote pancreatic stellate cell apoptosis and relieve pancreatic fibrosis by upregulating miR-15/16 in chronic pancreatitis
por: Ji, Ting, et al.
Publicado: (2020)

Role of pancreatic stellate cells in chemoresistance in pancreatic cancer
por: McCarroll, Joshua A., et al.
Publicado: (2014)

Subtypes of pancreatic stellate cells and distant metastasis of pancreatic ductal adenocarcinoma
por: Fan, Yuhui, et al.
Publicado: (2020)

Milk Fat Globule-EGF Factor 8 Alleviates Pancreatic Fibrosis by Inhibiting ER Stress-Induced Chaperone-Mediated Autophagy in Mice
por: Ren, Yifan, et al.
Publicado: (2021)

Cannabinoids Reduce Markers of Inflammation and Fibrosis in Pancreatic Stellate Cells
por: Michalski, Christoph W., et al.
Publicado: (2008)

Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells
por: Yan, Meizhu, et al.
Publicado: (2020)

Effects of Baicalin on inflammatory mediators and pancreatic acinar cell apoptosis in rats with sever acute pancreatitis
por: Xiping, Zhang, et al.
Publicado: (2009)

Molecular Mechanism of Pancreatic Stellate Cells Activation in Chronic Pancreatitis and Pancreatic Cancer
por: Jin, Guihua, et al.
Publicado: (2020)

Hydroxytyrosol Inhibits MDSCs and Promotes M1 Macrophages in Mice With Orthotopic Pancreatic Tumor
por: Wang, Botao, et al.
Publicado: (2021)

RNA-sequencing approach for exploring the protective mechanisms of dexmedetomidine on pancreatic injury in severe acute pancreatitis
por: Yao, Jiaqi, et al.
Publicado: (2023)

Inhibition of 5-Lipoxygenase in Hepatic Stellate Cells Alleviates Liver Fibrosis
por: Pu, Shiyun, et al.
Publicado: (2021)

Pancreatic stellate cell: Pandora's box for pancreatic disease biology
por: Bynigeri, Ratnakar R, et al.
Publicado: (2017)

A Rising Star in Pancreatic Diseases: Pancreatic Stellate Cells
por: Xue, Ran, et al.
Publicado: (2018)

Heterogeneous Pancreatic Stellate Cells Are Powerful Contributors to the Malignant Progression of Pancreatic Cancer
por: Zhang, Zhilin, et al.
Publicado: (2021)

Piezo1-mediated stellate cell activation causes pressure-induced pancreatic fibrosis in mice
por: Swain, Sandip M., et al.
Publicado: (2022)

Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis
por: Michalski, Christoph W, et al.
Publicado: (2007)

Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Han, Yuanyuan, et al.
Publicado: (2021)

Pancreatic stellate cells facilitate pancreatic cancer cell viability and invasion
por: Liu, Shang-Long, et al.
Publicado: (2019)

Biology of pancreatic stellate cells—more than just pancreatic cancer
por: Ferdek, Pawel E., et al.
Publicado: (2017)

Pancreatic stellate cells in pancreatic cancer: as potential targets for future therapy
por: Wang, Zhengfeng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mmet7v4073rdvi7f9vn4njj7k6