Cargando…

High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial (CARED-TRIAL)

OBJECTIVES: To evaluate whether a single high dose of oral cholecalciferol improves the respiratory outcomes as compared with placebo among adults COVID-19 patients at moderate risk of clinical complications. TRIAL DESIGN: The CARED trial is an investigator-initiated, multicentre, randomized, parall...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mariani, Javier, Tajer, Carlos, Antonietti, Laura, Inserra, Felipe, Ferder, León, Manucha, Walter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848249/ https://www.ncbi.nlm.nih.gov/pubmed/33522946 http://dx.doi.org/10.1186/s13063-021-05073-3

Ejemplares similares

Vitamin D supplementation: An alternative to enhance the effectiveness of vaccines against SARS-CoV-2?
por: Inserra, Felipe, et al.
Publicado: (2021)

Vitamin D high doses supplementation could represent a promising alternative to prevent or treat COVID-19 infection()
por: Mansur, José Luis, et al.
Publicado: (2020)

El suplemento con altas dosis de vitamina D podría representar una alternativa promisoria para prevenir o tratar la infección por COVID-19
por: Mansur, José Luis, et al.
Publicado: (2020)

Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment
por: Martín Giménez, Virna Margarita, et al.
Publicado: (2020)

High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: Multicentre randomized controlled clinical trial
por: Mariani, Javier, et al.
Publicado: (2022)

Vitamin D deficiency in African Americans is associated with a high risk of severe disease and mortality by SARS-CoV-2
por: Martín Giménez, Virna Margarita, et al.
Publicado: (2020)

Differences in RAAS/vitamin D linked to genetics and socioeconomic factors could explain the higher mortality rate in African Americans with COVID-19
por: Martín Giménez, Virna Margarita, et al.
Publicado: (2020)

Implications of Oxidative Stress and Potential Role of Mitochondrial Dysfunction in COVID-19: Therapeutic Effects of Vitamin D
por: de las Heras, Natalia, et al.
Publicado: (2020)

Multicap to improve adherence after acute coronary syndromes: results of a randomized controlled clinical trial
por: Mariani, Javier, et al.
Publicado: (2020)

Intramyocardial Dissecting Hematoma: A Mechanical Complication Needing Surgical Therapy?
por: Rossi Prat, Mauro, et al.
Publicado: (2022)

Potential Effects of Melatonin and Micronutrients on Mitochondrial Dysfunction during a Cytokine Storm Typical of Oxidative/Inflammatory Diseases
por: Martín Giménez, Virna Margarita, et al.
Publicado: (2021)

An adaptive randomised placebo controlled phase II trial of antivirals for COVID-19 infection (VIRCO): A structured summary of a study protocol for a randomised controlled trial
por: McMahon, James H., et al.
Publicado: (2020)

Trial summary and protocol for a phase II randomised placebo-controlled double-blinded trial of Interleukin 1 blockade in Acute Severe Colitis: the IASO trial
por: Thomas, Martin Geoffrey, et al.
Publicado: (2019)

Changes in renal WT-1 expression preceding hypertension development
por: Mazzei, Luciana, et al.
Publicado: (2016)

Placebo-controlled clinical trials: how trial documents justify the use of randomisation and placebo
por: Keränen, Tapani, et al.
Publicado: (2015)

Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial
por: Galan, Pilar, et al.
Publicado: (2010)

Impact of Maternal Daily Oral Low-Dose Vitamin A Supplementation on the Mother-Infant Pair: A Randomised Placebo-Controlled Trial in China
por: Ding, Ye, et al.
Publicado: (2021)

The use of placebo in randomised surgical clinical trials
por: Wartolowska, Karolina, et al.
Publicado: (2013)

L-arginine and Vitamin D Adjunctive Therapies in Pulmonary Tuberculosis: A Randomised, Double-Blind, Placebo-Controlled Trial
por: Ralph, Anna P., et al.
Publicado: (2013)

The effect of infant vitamin B(12) supplementation on neurodevelopment: a follow-up of a randomised placebo-controlled trial in Nepal
por: Ulak, Manjeswori, et al.
Publicado: (2023)

Ethical considerations in placebo-controlled randomised clinical trials
por: Kaufman, Kenneth R.
Publicado: (2015)

The importance of using placebo controls in nonpharmacological randomised trials
por: Wartolowska, Karolina A., et al.
Publicado: (2023)

A prospective, randomised, double blind placebo-controlled trial to evaluate the efficacy and safety of tocilizumab in patients with severe COVID-19 pneumonia (TOC-COVID): A structured summary of a study protocol for a randomised controlled trial
por: Rilinger, Jonathan, et al.
Publicado: (2020)

Vitamins C and E for prevention of pre-eclampsia in women with type 1 diabetes (DAPIT): a randomised placebo-controlled trial
por: McCance, David R, et al.
Publicado: (2010)

Vitamin D supplementation for treatment of seasonal affective symptoms in healthcare professionals: a double-blind randomised placebo-controlled trial
por: Frandsen, Tenna Bloch, et al.
Publicado: (2014)

Vitamin D to prevent acute lung injury following oesophagectomy (VINDALOO): study protocol for a randomised placebo controlled trial
por: Parekh, Dhruv, et al.
Publicado: (2013)

Vitamin D in the prevention of exacerbations of asthma in preschoolers (DIVA): protocol for a multicentre randomised placebo-controlled triple-blind trial
por: Jensen, Megan E, et al.
Publicado: (2019)

The additive effect of vitamin K supplementation and bisphosphonate on fracture risk in post-menopausal osteoporosis: a randomised placebo controlled trial
por: Moore, Amelia E., et al.
Publicado: (2023)

Rizatriptan vs. ibuprofen in migraine: a randomised placebo-controlled trial
por: Misra, Usha Kant, et al.
Publicado: (2007)

Tiotropium treatment for bronchiectasis: a randomised, placebo-controlled, crossover trial
por: Jayaram, Lata, et al.
Publicado: (2022)

The Microbiome of Infants Recruited to a Randomised Placebo-controlled Probiotic Trial (PiPS Trial)
por: Millar, Michael, et al.
Publicado: (2017)

Magnesium for aneurysmal subarachnoid haemorrhage (MASH-2): a randomised placebo-controlled trial
por: Mees, Sanne M Dorhout, et al.
Publicado: (2012)

A quadruple blinded placebo controlled randomised trial to evaluate the effectiveness of an Iodine complex for patients with mild to moderate COVID-19 in Pakistan (I-COVID-PK): A structured summary of a study protocol for a randomised controlled trial
por: Ashraf, Sohaib, et al.
Publicado: (2021)

The BREATHE study: Breathing REtraining for Asthma — Trial of Home Exercises. A protocol summary of a randomised controlled trial
por: Bruton, Anne, et al.
Publicado: (2013)

The effect of homocysteine-lowering with B-vitamins on osteoporotic fractures in patients with cerebrovascular disease: substudy of VITATOPS, a randomised placebo-controlled trial
por: Gommans, John, et al.
Publicado: (2013)

Efficacy of Vitamin C Vaginal Tablets as Prophylaxis for Recurrent Bacterial Vaginosis: A Randomised, Double-Blind, Placebo-Controlled Clinical Trial
por: Krasnopolsky, Vladislav N., et al.
Publicado: (2013)

Study protocol: a randomised placebo-controlled clinical trial to study the effect of vitamin D supplementation on glycaemic control in type 2 Diabetes Mellitus SUNNY trial
por: Krul-Poel, Yvonne HM, et al.
Publicado: (2014)

Vitamin D(3) and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial): study protocol for a randomised placebo-controlled trial
por: Dzavakwa, Nyasha Veronica, et al.
Publicado: (2022)

A Summary of the ADVANCE Trial
por: Heller, Simon R.
Publicado: (2009)

Suicide attempts in clinical trials with paroxetine randomised against placebo
por: Aursnes, Ivar, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_2jr7tjb0d8jjhh8h2m8euaerl4