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Knockdown of IARS2 Inhibited Proliferation of Acute Myeloid Leukemia Cells by Regulating p53/p21/PCNA/eIF4E Pathway

IARS2 encodes mitochondrial isoleucine-tRNA synthetase, which mutation may cause multiple diseases. However, the biological function of IARS2 on acute myeloid leukemia (AML) has not yet been identified. In the present study, qRT-PCR was used to determine the expression of IARS2 in K562, THP1, and HL...

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Detalles Bibliográficos
Autores principales:	Li, Hong, Tian, Yaning, Li, Xiang, Wang, Bin, Zhai, Dongzhi, Bai, Yingying, Dong, Changhu, Chao, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cognizant Communication Corporation 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848268/ https://www.ncbi.nlm.nih.gov/pubmed/30832756 http://dx.doi.org/10.3727/096504018X15426261956343

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