CRISPR/Cas9-Mediated Gene Knockout of ARID1A Promotes Primary Progesterone Resistance by Downregulating Progesterone Receptor B in Endometrial Cancer Cells

Medroxyprogesterone (MPA) is used for the conservative treatment of endometrial cancer. Unfortunately, progesterone resistance seriously affects its therapeutic effect. The purpose of the current study was to investigate the influence of deletion of AT-rich interactive domain 1A (ARID1A) in progeste...

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Detalles Bibliográficos
Autores principales: Wang, Haizhen, Tang, Zhenghua, Li, Ting, Liu, Menglu, Li, Yong, Xing, Baoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848330/
https://www.ncbi.nlm.nih.gov/pubmed/31072420
http://dx.doi.org/10.3727/096504019X15561873320465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848330/
https://www.ncbi.nlm.nih.gov/pubmed/31072420
http://dx.doi.org/10.3727/096504019X15561873320465

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