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Retrospective study of dilated cardiomyopathy in dogs
BACKGROUND: The United States Food and Drug Administration is investigating possible diet‐associated dilated cardiomyopathy (DCM) in dogs and cats. OBJECTIVES: To retrospectively review DCM cases for signalment, diet information, echocardiographic changes, and survival. ANIMALS: Client‐owned dogs (n...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848368/ https://www.ncbi.nlm.nih.gov/pubmed/33345431 http://dx.doi.org/10.1111/jvim.15972 |
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author | Freid, Kimberly J. Freeman, Lisa M. Rush, John E. Cunningham, Suzanne M. Davis, Megan S. Karlin, Emily T. Yang, Vicky K. |
author_facet | Freid, Kimberly J. Freeman, Lisa M. Rush, John E. Cunningham, Suzanne M. Davis, Megan S. Karlin, Emily T. Yang, Vicky K. |
author_sort | Freid, Kimberly J. |
collection | PubMed |
description | BACKGROUND: The United States Food and Drug Administration is investigating possible diet‐associated dilated cardiomyopathy (DCM) in dogs and cats. OBJECTIVES: To retrospectively review DCM cases for signalment, diet information, echocardiographic changes, and survival. ANIMALS: Client‐owned dogs (n = 71). METHODS: Medical records of dogs diagnosed with DCM between January 1, 2014 and September 30, 2018 were reviewed. Dogs were grouped into “traditional” or “nontraditional” diet categories and whether or not diet was changed after diagnosis. RESULTS: For dogs eating nontraditional diets, those that had their diets changed had a larger percentage decrease in normalized systolic left ventricular internal dimension (P = .03) and left atrial:aorta ratio (P < .001) compared to those that did not have their diets changed. Survival time was significantly longer for dogs with DCM eating nontraditional diets that had their diets changed (median survival, 337 days; range, 9‐1307 days) compared to dogs eating nontraditional diets that did not have their diets changed (median survival, 215 days; range, 1‐852 days; P = .002). CONCLUSIONS AND CLINICAL IMPORTANCE: Dogs with DCM eating nontraditional diets can experience improvement in cardiac function after diet change but additional research is needed to examine possible associations between diet and DCM. |
format | Online Article Text |
id | pubmed-7848368 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78483682021-02-05 Retrospective study of dilated cardiomyopathy in dogs Freid, Kimberly J. Freeman, Lisa M. Rush, John E. Cunningham, Suzanne M. Davis, Megan S. Karlin, Emily T. Yang, Vicky K. J Vet Intern Med SMALL ANIMAL BACKGROUND: The United States Food and Drug Administration is investigating possible diet‐associated dilated cardiomyopathy (DCM) in dogs and cats. OBJECTIVES: To retrospectively review DCM cases for signalment, diet information, echocardiographic changes, and survival. ANIMALS: Client‐owned dogs (n = 71). METHODS: Medical records of dogs diagnosed with DCM between January 1, 2014 and September 30, 2018 were reviewed. Dogs were grouped into “traditional” or “nontraditional” diet categories and whether or not diet was changed after diagnosis. RESULTS: For dogs eating nontraditional diets, those that had their diets changed had a larger percentage decrease in normalized systolic left ventricular internal dimension (P = .03) and left atrial:aorta ratio (P < .001) compared to those that did not have their diets changed. Survival time was significantly longer for dogs with DCM eating nontraditional diets that had their diets changed (median survival, 337 days; range, 9‐1307 days) compared to dogs eating nontraditional diets that did not have their diets changed (median survival, 215 days; range, 1‐852 days; P = .002). CONCLUSIONS AND CLINICAL IMPORTANCE: Dogs with DCM eating nontraditional diets can experience improvement in cardiac function after diet change but additional research is needed to examine possible associations between diet and DCM. John Wiley & Sons, Inc. 2020-12-21 2021 /pmc/articles/PMC7848368/ /pubmed/33345431 http://dx.doi.org/10.1111/jvim.15972 Text en © 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | SMALL ANIMAL Freid, Kimberly J. Freeman, Lisa M. Rush, John E. Cunningham, Suzanne M. Davis, Megan S. Karlin, Emily T. Yang, Vicky K. Retrospective study of dilated cardiomyopathy in dogs |
title | Retrospective study of dilated cardiomyopathy in dogs |
title_full | Retrospective study of dilated cardiomyopathy in dogs |
title_fullStr | Retrospective study of dilated cardiomyopathy in dogs |
title_full_unstemmed | Retrospective study of dilated cardiomyopathy in dogs |
title_short | Retrospective study of dilated cardiomyopathy in dogs |
title_sort | retrospective study of dilated cardiomyopathy in dogs |
topic | SMALL ANIMAL |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848368/ https://www.ncbi.nlm.nih.gov/pubmed/33345431 http://dx.doi.org/10.1111/jvim.15972 |
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