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E2-Induced Activation of the NLRP3 Inflammasome Triggers Pyroptosis and Inhibits Autophagy in HCC Cells

Emerging evidence suggests that 17β-estradiol (E2) and estrogen receptor (ER) signaling are protective against hepatocellular carcinoma (HCC). In our previous study, we showed that E2 suppressed the carcinogenesis and progression of HCC by targeting NLRP3 inflammasome activation, whereas the molecul...

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Detalles Bibliográficos
Autores principales: Wei, Qing, Zhu, Rui, Zhu, Junying, Zhao, Rongping, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848400/
https://www.ncbi.nlm.nih.gov/pubmed/30940293
http://dx.doi.org/10.3727/096504018X15462920753012