Cargando…

Silencing Artemis Enhances Colorectal Cancer Cell Sensitivity to DNA-Damaging Agents

Artemis is a key protein of NHEJ (nonhomologous end joining), which is the major pathway for the repair of IR-induced DSBs in mammalian cells. However, the expression of Artemis in tumors and the influence of silencing Artemis on tumor sensitivity to radiation have not been investigated fully. In th...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Hai, Wang, Xuanxuan, Huang, Aihua, Gao, Huaping, Sun, Yikan, Jiang, Tingting, Shi, Liming, Wu, Xianjie, Dong, Qinghua, Sun, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848410/
https://www.ncbi.nlm.nih.gov/pubmed/29426373
http://dx.doi.org/10.3727/096504018X15179694020751