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Silencing Artemis Enhances Colorectal Cancer Cell Sensitivity to DNA-Damaging Agents
Artemis is a key protein of NHEJ (nonhomologous end joining), which is the major pathway for the repair of IR-induced DSBs in mammalian cells. However, the expression of Artemis in tumors and the influence of silencing Artemis on tumor sensitivity to radiation have not been investigated fully. In th...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cognizant Communication Corporation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848410/ https://www.ncbi.nlm.nih.gov/pubmed/29426373 http://dx.doi.org/10.3727/096504018X15179694020751 |