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Synergistic Efficacy of the Demethylation Agent Decitabine in Combination With the Protease Inhibitor Bortezomib for Treating Multiple Myeloma Through the Wnt/β-Catenin Pathway
Multiple myeloma (MM) is a hematopoietic malignancy characterized by the clonal proliferation of antibody-secreting plasma cells. Bortezomib (BZM), the first FDA-approved proteasome inhibitor, has significant antimyeloma activity and prolongs the median survival of MM patients. However, MM remains i...
Autores principales: | Jin, Yulong, Xu, Li, Wu, Xiaodong, Feng, Juan, Shu, Mimi, Gu, Hongtao, Gao, Guangxun, Zhang, Jinyi, Dong, Baoxia, Chen, Xiequn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cognizant Communication Corporation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848415/ https://www.ncbi.nlm.nih.gov/pubmed/30837032 http://dx.doi.org/10.3727/096504018X15443011011637 |
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