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Overexpression of Pyruvate Dehydrogenase E1α Subunit Inhibits Warburg Effect and Induces Cell Apoptosis Through Mitochondria-Mediated Pathway in Hepatocellular Carcinoma

Most cancers rely disproportionately on glycolysis for energy even in the presence of an adequate oxygen supply, a condition known as “aerobic glycolysis,” or the “Warburg effect.” Pyruvate dehydrogenase E1α subunit (PDHA1) is one of the main factors for the metabolic switch from oxidative phosphory...

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Detalles Bibliográficos
Autores principales:	Sun, Jihong, Li, Jingjing, Guo, Zhixian, Sun, Lu, Juan, Chenghui, Zhou, Yubing, Gu, Hongli, Yu, Yan, Hu, Qiuyue, Kan, Quancheng’, Yu, Zujiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cognizant Communication Corporation 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848459/ https://www.ncbi.nlm.nih.gov/pubmed/29444744 http://dx.doi.org/10.3727/096504018X15180451872087

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