Structural effects of stabilization and complexation of a zinc-deficient superoxide dismutase

The activity of the erythrocyte Cu(2),Zn(2)-superoxide dismutase (SOD1) is altered in Alzheimer's disease (AD) patients. These patients, compared to healthy subjects, exhibit low plasmatic zinc (Zn) levels in the presence of high plasmatic levels of copper (Cu). SOD1 is an antioxidant enzyme ch...

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Detalles Bibliográficos
Autores principales: Manieri, Tania M., Sensi, Stefano L., Squitti, Rosanna, Cerchiaro, Giselle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848637/
https://www.ncbi.nlm.nih.gov/pubmed/33553758
http://dx.doi.org/10.1016/j.heliyon.2021.e06100

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