Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients

Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1–7 formation https://bit.ly/2MU1z4z

Detalles Bibliográficos
Autores principales: van Lier, Dirk, Kox, Matthijs, Santos, Karine, van der Hoeven, Hans, Pillay, Janesh, Pickkers, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848790/
https://www.ncbi.nlm.nih.gov/pubmed/33738305
http://dx.doi.org/10.1183/23120541.00848-2020
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author van Lier, Dirk
Kox, Matthijs
Santos, Karine
van der Hoeven, Hans
Pillay, Janesh
Pickkers, Peter
author_facet van Lier, Dirk
Kox, Matthijs
Santos, Karine
van der Hoeven, Hans
Pillay, Janesh
Pickkers, Peter
author_sort van Lier, Dirk
collection PubMed
description Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1–7 formation https://bit.ly/2MU1z4z
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spelling pubmed-78487902021-02-02 Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients van Lier, Dirk Kox, Matthijs Santos, Karine van der Hoeven, Hans Pillay, Janesh Pickkers, Peter ERJ Open Res Original Research Letters Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1–7 formation https://bit.ly/2MU1z4z European Respiratory Society 2021-03-15 /pmc/articles/PMC7848790/ /pubmed/33738305 http://dx.doi.org/10.1183/23120541.00848-2020 Text en Copyright ©The authors 2021 http://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org)
spellingShingle Original Research Letters
van Lier, Dirk
Kox, Matthijs
Santos, Karine
van der Hoeven, Hans
Pillay, Janesh
Pickkers, Peter
Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients
title Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients
title_full Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients
title_fullStr Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients
title_full_unstemmed Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients
title_short Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients
title_sort increased blood angiotensin converting enzyme 2 activity in critically ill covid-19 patients
topic Original Research Letters
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848790/
https://www.ncbi.nlm.nih.gov/pubmed/33738305
http://dx.doi.org/10.1183/23120541.00848-2020
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