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Oesophageal squamous cell carcinoma–associated IL‐33 rewires macrophage polarization towards M2 via activating ornithine decarboxylase

BACKGROUND: The tumour microenvironment primarily constitutes macrophages in the form of an immunosuppressive M2 phenotype, which promotes tumour growth. Thus, the development of methodologies to rewire M2‐like tumour‐associated macrophages (TAMs) into the M1 phenotype, which inhibits tumour growth,...

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Detalles Bibliográficos
Autores principales: Mai, Shijie, Liu, Le, Jiang, Jianjun, Ren, Pengfei, Diao, Dingwei, Wang, Haofei, Cai, Kaican
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848962/
https://www.ncbi.nlm.nih.gov/pubmed/33305406
http://dx.doi.org/10.1111/cpr.12960