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Cefiderocol Retains Antibiofilm Activity in Multidrug-Resistant Gram-Negative Pathogens

Cefiderocol is a siderophore cephalosporin with potent antibacterial activity against a broad range of Gram-negative pathogens, including multidrug-resistant strains. Siderophore antibiotics bind ferric iron and utilize iron transporters to cross the cell membrane. In the biofilm setting, where anti...

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Detalles Bibliográficos
Autores principales: Pybus, Christine A., Felder-Scott, Christina, Obuekwe, Victor, Greenberg, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849010/
https://www.ncbi.nlm.nih.gov/pubmed/33199383
http://dx.doi.org/10.1128/AAC.01194-20