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Distinct profile of CD34(+) cells and plasma-derived extracellular vesicles from triple-negative patients with Myelofibrosis reveals potential markers of aggressive disease

BACKGROUND: Myelofibrosis (MF) is a clonal disorder of hemopoietic stem/progenitor cells (HSPCs) with high prevalence in elderly patients and mutations in three driver genes (JAK2, MPL, or CALR). Around 10–15% of patients are triple-negative (TN) for the three driver mutations and display significan...

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Detalles Bibliográficos
Autores principales: Forte, Dorian, Barone, Martina, Morsiani, Cristina, Simonetti, Giorgia, Fabbri, Francesco, Bruno, Samantha, Bandini, Erika, Sollazzo, Daria, Collura, Salvatore, Deregibus, Maria Chiara, Auteri, Giuseppe, Ottaviani, Emanuela, Vianelli, Nicola, Camussi, Giovanni, Franceschi, Claudio, Capri, Miriam, Palandri, Francesca, Cavo, Michele, Catani, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849077/
https://www.ncbi.nlm.nih.gov/pubmed/33522952
http://dx.doi.org/10.1186/s13046-020-01776-8