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Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disorder with no absolute cure. The evidence of the involvement of gut microbiota in PD pathogenesis suggests the need to identify certain molecule(s) derived from the gut microbiota, which has the potential to manage PD. Osteocalcin (OCN),...

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Detalles Bibliográficos
Autores principales:	Hou, Yan-fang, Shan, Chang, Zhuang, Si-yue, Zhuang, Qian-qian, Ghosh, Arijit, Zhu, Ke-cheng, Kong, Xiao-ke, Wang, Shu-min, Gong, Yan-ling, Yang, Yu-ying, Tao, Bei, Sun, Li-hao, Zhao, Hong-Yan, Guo, Xing-zhi, Wang, Wei-qing, Ning, Guang, Gu, Yan-yun, Li, Sheng-tian, Liu, Jian-min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849090/ https://www.ncbi.nlm.nih.gov/pubmed/33517890 http://dx.doi.org/10.1186/s40168-020-00988-6

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