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Predictive modeling of single-cell DNA methylome data enhances integration with transcriptome data

Single-cell DNA methylation data has become increasingly abundant and has uncovered many genes with a positive correlation between expression and promoter methylation, challenging the common dogma based on bulk data. However, computational tools for analyzing single-cell methylome data are lagging f...

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Detalles Bibliográficos
Autores principales: Uzun, Yasin, Wu, Hao, Tan, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849382/
https://www.ncbi.nlm.nih.gov/pubmed/33219054
http://dx.doi.org/10.1101/gr.267047.120