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Gene expression imputation and cell-type deconvolution in human brain with spatiotemporal precision and its implications for brain-related disorders

As the most complex organ of the human body, the brain is composed of diverse regions, each consisting of distinct cell types and their respective cellular interactions. Human brain development involves a finely tuned cascade of interactive events. These include spatiotemporal gene expression change...

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Detalles Bibliográficos
Autores principales: Pei, Guangsheng, Wang, Yin-Ying, Simon, Lukas M., Dai, Yulin, Zhao, Zhongming, Jia, Peilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849392/
https://www.ncbi.nlm.nih.gov/pubmed/33272935
http://dx.doi.org/10.1101/gr.265769.120