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Gene expression imputation and cell-type deconvolution in human brain with spatiotemporal precision and its implications for brain-related disorders
As the most complex organ of the human body, the brain is composed of diverse regions, each consisting of distinct cell types and their respective cellular interactions. Human brain development involves a finely tuned cascade of interactive events. These include spatiotemporal gene expression change...
Autores principales: | Pei, Guangsheng, Wang, Yin-Ying, Simon, Lukas M., Dai, Yulin, Zhao, Zhongming, Jia, Peilin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849392/ https://www.ncbi.nlm.nih.gov/pubmed/33272935 http://dx.doi.org/10.1101/gr.265769.120 |
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